Let’s not beat around the bush. Here are four simple but hard hitting findings about the red wine ingredient Resveratrol that you NEED to know.
1. Imitator of caloric restriction.
Resveratrol consumption stimulates the production of adiponectin, which is a commonly measured bio-marker in humans practicing caloric restriction (by more than 30%). Adiponectin is a protein that is actively involved in fatty acid breakdown and regulating blood sugar levels.
The other common denominator between caloric restriction and Resveratrol is their ability to facilitate autophagy through inhibition of mammalian target of rapamycin. This means your body kills off any cellular components that aren’t working properly and a healthier you surfaces.
2. Natural testosterone booster in men/ Possible menopause treatment for women.
Natural testosterone production is significantly increased through Resveratrol consumption. It acts as a selective estrogen receptor modulator and an aromatase inhibitor. This results in the interference of estrogen production in men and creates a better environment for muscle building with more readily available testosterone.
Don’t worry girls, it does not have an identical effect for you. In women, Resveratrol works by mimicking estrogen in the brain and has been suggested to be a possible treatment for women suffering symptoms of menopause by improving blood flow to the brain and balancing hormone metabolism.
3. Enhances Mitochondria function.
Mitochondria are the powerhouse of your cells and are crucial for metabolic homeostasis. They generate the energy needed for our cells to do their jobs and if they are not functioning properly, energy production and internal homeostasis is impaired.
Resveratrol consumption is associated with the induction of genes for oxidative phosphorylation and mitochondrial biogenesis. This means that it assists in the creation of mitochondria and assists with its function. Lagouge et al. (2006) concluded that because of these effects, as well evidence of increased energy homeostasis in research subjects, genes activated by Resveratrol consumption is a key regulator of energy and metabolic homeostasis.
4. Imitates the response to exercise.
Exercise creates a physiological stress on the body, resulting in mechanisms that breakdown fat and sugar for use as energy and also promote blood flow to organs and muscle for oxygen and nutrient delivery.
Resveratrol consumption results in hormone and physiological responses that are also shown in response to physiological stress and exercise. Many pf these are previously mentioned but here they are again with some added:
- Fatty acid breakdown and fat metabolism (adiponectin production).
- Blood sugar control (adiponectin production and GLUT4 stimulation)
- Enhanced muscle building capacity (testosterone production).
- Enhanced cognition (hormone metabolism, estrogen effects in brain, nitric oxide production for enhanced cerebral blood flow).
- Better nutrient delivery to cells (nitric oxide production and vasodilation).
- Energy production and utilisation (mitochondria production and enhanced function).
Many trials have reported the positive effects Resveratrol provides for healthy body functioning. We aren’t saying this is a miracle ingredient or that you should stop exercising or living a healthy and active lifestyle, we are just giving you an insight into this powerhouse ingredient. Our suggestion? Consume Resveratrol daily in conjunction with a healthy diet and active lifestyle.
Our Exerstend ‘Advanced Diet & Blood Sugar Support’ product contains 200 mg (one of the highest doses on the market) of pure Resveratrol. We have combined it with Magnesium and Zinc to help you feel mobile and healthy whilst getting as many of the positive benefits of exercise before you even hit the treadmill!
Kaeberlein M, McDonagh T, Heltweg B, Hixon J, Westman EA, Caldwell SD, Napper A, Curtis R, DiStefano PS, Fields S, Bedalov A, Kennedy BK; McDonagh; Heltweg; Hixon; Westman; Caldwell; Napper; Curtis; Distefano; Fields; Bedalov; Kennedy (April 2005). “Substrate-specific activation of sirtuins by resveratrol”. J. Biol. Chem. 280 (17): 17038–45. doi:10.1074/jbc.M500655200. PMID 15684413.
Li H, Xia N, Förstermann U. Cardiovascular effects and molecular targets of resveratrol. Nitric Oxide. 2012;26(2):102-10.
Bhat KP, Lantvit D, Christov K, Mehta RG, Moon RC, Pezzuto JM; Lantvit; Christov; Mehta; Moon; Pezzuto (October 2001). “Estrogenic and antiestrogenic properties of resveratrol in mammary tumor models”. Cancer Res. 61 (20): 7456–63. PMID 11606380.
Lagouge M, Argmann C, Gerhart-Hines Z, Meziane H, Lerin C, Daussin F, Messadeq N, Milne J, Lambert P, Elliott P, Geny B, Laakso M, Puigserver P, Auwerx J; Argmann; Gerhart-Hines; Meziane; Lerin; Daussin; Messadeq; Milne; Lambert; Elliott; Geny; Laakso; Puigserver; Auwerx (December 2006). “Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha”. Cell 127 (6): 1109–22. doi:10.1016/j.cell.2006.11.013. PMID 17112576.